Appeal No. 2006-3105 Application No. 09/397,494 Layne teaches all of the limitations recited in independent claim 26 including the probe array experiment. The Summary of the Invention of Layne teaches that the process controller translates user commands into test suite commands and for communicating results to the user. In column 8 of Layne, the discussion of Figure 4 teaches the use of a remote automated testing and analysis capability and the use of the Internet. The communication to the remote lab includes instructions enabling program control tools to define and perform automated tests. Therefore, we find that Layne alone teaches and fairly suggests the method of independent claim 26. Furthermore, the Examiner has combined the teachings of Dehlinger with respect to the use of a “probe array” which is more akin to that which Appellants disclose in the specification. We agree with the Examiner that it would have been obvious to one skilled in the art at the time of the invention to have implemented the methodology of Layne with various probes and their corresponding experiments since this does not change the method, but only the range of experiments that the method may be adapted to control. Here, we find that the Examiner has established a prima facie case of obviousness for the combined teachings of Layne and Dehlinger. Therefore, we look to Appellants’ briefs to identify an error in the Examiner’s prima facie case. Appellants argue that the probe array experiments performed in accordance with the claimed embodiments utilize a radically different technology that differs in significant ways from the robotic microtiter technology of Layne et al. '731. One important difference between these technologies, is the vastly increased data volumes data expected to result from the probe array experiments conducted in accordance with the present invention. For example, while Layne et al. '731 describe an experiment comprising at most ninety-six (96) wells at a time, Dehlinger '320 describes experiments in which data is simultaneously collected from large arrays comprising thousands of probes (Br. 6). 7Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 NextLast modified: November 3, 2007