Appeal 2006-2686 Application 09/994,495 openings, respectively (id.). The Examiner applies Sanadi for the teaching to avoid the problem of cross-contamination of an array of tube or multi- well plates by sealing the openings associated with the array of tubes or wells by a variety of sealing devices, such as plates, tapes, and caps (Answer 8-9). From these findings, the Examiner concludes that it would have been obvious to one of ordinary skill in the art at the time of the invention to employ the sealing devices disclosed by Sanadi to seal the openings of an array device such as disclosed by McGraw to prevent contamination of the wells of the array device (Answer 9). Appellants argue that the combination of McGraw with Sanadi is improper because there is no motivation or suggestion supporting the combination since McGraw does not suggest sealing any opening but requires that the inlet and outlet openings remain open (Br. 27). Appellants argue that Sanadi requires one closed end and one open end, and thus there would be no motivation to combine this disclosure with the teachings of McGraw (Br. 28-29). Finally, Appellants argue that assuming such a motivation does exist, the modification would render McGraw unsatisfactory for its intended purpose (Br. 29). Appellants’ arguments are not persuasive. As correctly argued by the Examiner, McGraw requires the inlet and outlet openings to remain open during processing but one of ordinary skill in this art would have readily recognized that sealing the inlet and outlet openings prior to or after processing would have prevented contamination of the device contents, as taught by Sanadi (Answer 19-20). Accordingly, the use of first and second sealing devices for the first and second end openings, respectively, would 10Page: Previous 1 2 3 4 5 6 7 8 9 10 11 Next
Last modified: September 9, 2013