Ex Parte Somack et al - Page 10

                Appeal 2006-2686                                                                                
                Application 09/994,495                                                                          
                openings, respectively (id.).  The Examiner applies Sanadi for the teaching                     
                to avoid the problem of cross-contamination of an array of tube or multi-                       
                well plates by sealing the openings associated with the array of tubes or                       
                wells by a variety of sealing devices, such as plates, tapes, and caps (Answer                  
                8-9).  From these findings, the Examiner concludes that it would have been                      
                obvious to one of ordinary skill in the art at the time of the invention to                     
                employ the sealing devices disclosed by Sanadi to seal the openings of an                       
                array device such as disclosed by McGraw to prevent contamination of the                        
                wells of the array device (Answer 9).                                                           
                       Appellants argue that the combination of McGraw with Sanadi is                           
                improper because there is no motivation or suggestion supporting the                            
                combination since McGraw does not suggest sealing any opening but                               
                requires that the inlet and outlet openings remain open (Br. 27).  Appellants                   
                argue that Sanadi requires one closed end and one open end, and thus there                      
                would be no motivation to combine this disclosure with the teachings of                         
                McGraw (Br. 28-29).  Finally, Appellants argue that assuming such a                             
                motivation does exist, the modification would render McGraw unsatisfactory                      
                for its intended purpose (Br. 29).                                                              
                       Appellants’ arguments are not persuasive.  As correctly argued by the                    
                Examiner, McGraw requires the inlet and outlet openings to remain open                          
                during processing but one of ordinary skill in this art would have readily                      
                recognized that sealing the inlet and outlet openings prior to or after                         
                processing would have prevented contamination of the device contents, as                        
                taught by Sanadi (Answer 19-20).  Accordingly, the use of first and second                      
                sealing devices for the first and second end openings, respectively, would                      



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