Appeal No. 2006-3254 Application No. 10/347,982 Appellants argue that the “even more significant advance is the relatively non-irritating nature of the malonate salts.” (Id.) We are not persuaded by these arguments. We note initially that whether Jokura or Günter describes treating the signs of aging is not relevant to whether the Examiner has set forth a prima facie case of obviousness. Prima facie obviousness does not require prior art references to recognize or even suggest the problem that Appellants attempted to solve. In addition, the prior art does not have to teach combining references for the reason that Appellants combined them. In re Dillon, 919 F.2d 688, 692-93, 16 USPQ2d 1897, 1901 (Fed. Cir. 1990, en banc). In addition, we conclude that Appellants have not set forth sufficient evidence of unexpectedly superior results to rebut the prima facie case that claim 1 would have been obvious. In particular, Appellants have not shown that the claimed composition has unexpectedly superior results as compared to the closest prior art. “[W]hen unexpected results are used as evidence of nonobviousness, the results must be shown to be unexpected compared with the closest prior art.” In re Baxter-Travenol Labs., 952 F.2d 388, 392, 21 USPQ2d 1281, 1285 (Fed. Cir. 1991). We conclude that the Examiner has set forth a prima facie case that claim 1 would have been obvious over Jokura in view of Günter, which Appellants have not rebutted. We therefore affirm the rejection of claim 1 under 35 U.S.C. § 103. Claims 4 and 5 fall with claim 1. 10Page: Previous 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 Next
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