Ex Parte Perricone - Page 9

                Appeal No. 2006-3372                                                                           
                Application No. 10/454,521                                                                     

                Id.                                                                                            
                      Appellant argues that Martin does not suggest a claim that requires                      
                tocotrienol in addition to lipoic acid and α-hydroxy acid ingredients (Br. 11).                
                According to appellant, “[a]lone or in combination, the cited references                       
                point away from using lipoic acid and α-hydroxy acid with tocotrienol . . . to                 
                treat rosacea.”  Id. at 12-13.                                                                 
                      Appellant is essentially arguing that Martin does not remedy the                         
                deficiencies of McAtee.  Thus, this rejection is affirmed for the reasons set                  
                forth above with respect to the anticipation rejection over McAtee.                            
                                     NEW GROUND OF REJECTION                                                   
                      Under the provisions of 37 CFR § 41.50(b), we enter the following                        
                new ground of rejection: Claim 10 is rejected under 35 U.S.C.                                  
                § 103(a) as being obvious over the combination of McAtee and Duffy.4                           
                      As noted above with respect to the rejection of claim 10 as being                        
                obvious over McAtee, McAtee teaches the inclusion of vitamin C and its                         
                derivatives in the skin care compositions disclosed by that reference (col. 10,                
                ll. 51-55).  McAtee, however, does not specifically teach or suggest the use                   
                of a fatty acid ester of vitamin C as the derivative of vitamin C.                             
                      Duffy teaches the use of vitamin C or one or more of its derivatives to                  
                decrease the skin irritation caused by the topical administration of an active                 
                ingredient such as α-hydroxy acids (abstract).  Duffy teaches that a                           
                derivative of ascorbic acid that may be used is ascorbyl palmitate, a fatty                    
                acid ester of vitamin C (col. 4, ll. 15-35).                                                   

                                                                                                              
                4 Duffy, U.S. Patent No. 5,703,122, issued December 30, 1997.                                  

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