Ex Parte Baker et al - Page 3

                 Appeal No. 2007-0083                                                                                 
                 Application No. 10/174,574                                                                           

                        proteins  having  homology  thereto,  are  of  interest  to  the                              
                        scientific and medical communities.                                                           
                        We herein describe the identification and characterization of                                 
                        novel polypeptides having homology to thioredoxin, designated                                 
                        herein as PRO270 polypeptides.                                                                
                 Page 25.                                                                                             
                                                   DISCUSSION                                                         
                 1.  CLAIMS                                                                                           
                        Claims 25-29 are pending and on appeal.  The claims have not been                             
                 argued separately; therefore, they stand or fall together.  37 CFR                                   
                 § 41.37(c)(1)(vii).  Claim 25 is representative and reads as follows:                                
                        25. An isolated antibody that binds specifically to the polypeptide                           
                               of SEQ ID NO:32.                                                                       
                 2.  UTILITY                                                                                          
                        Claims 25-29 stand rejected under 35 U.S.C. §§ 101 and 112, first                             
                 paragraph, as lacking patentable utility.  The Examiner argues that claimed                          
                 antibodies lack utility because PRO270 lacks utility.  In particular, the                            
                 Examiner argues that the disclosed similarity between PRO270 and                                     
                 thioredoxin is not enough, by itself, to establish PRO270’s utility:                                 
                        [T]he mere identification that a protein belongs to a family of                               
                        proteins,  while  indicative  of  evolutionary  relatedness,  is  not                         
                        indicative of function, nor by extension of utility. . . .  [W]ithout                         
                        any information as to the specific properties of the protein, the                             
                        mere identification of such as having homology to thioredoxin                                 
                        proteins is not sufficient to impart any particular utility to the                            
                        polypeptide.                                                                                  
                 Examiner’s Answer, page 4.                                                                           


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