Ex Parte Davis et al - Page 3

                 Appeal 2007-0181                                                                                     
                 Application 10/057,323                                                                               
                                                   DISCUSSION                                                         
                        The Examiner rejected claims 1-4, 11-13, 37-40, 42, 43, 47, 48, 83,                           
                 84, and 86 under 35 U.S.C. § 103(a) as being obvious over the combination                            
                 of Rosenblum and Medical Letter (Answer 4).  As Appellants do not argue                              
                 the claims separately, we focus our analysis on independent claim 1.  Merely                         
                 pointing out differences in what the claims cover is not an argument as to                           
                 why the claims are separately patentable.  37 CFR § 41.37(c)(1)(vii).                                
                        Rosenblum is cited for teaching ezetimibe is useful for reducing                              
                 cholesterol levels and the risk of atherosclerosis (Answer 4).  Medical Letter                       
                 is cited for teaching that fenofibrate is useful in reducing serum cholesterol                       
                 levels (id.).  The Examiner acknowledges that “[t]he references do not                               
                 expressly teach a composition containing fenifibrate and ezetimibe                                   
                 together.”  (Id.)                                                                                    
                        The Examiner concludes, however:                                                              
                               It would have been obvious to one of ordinary skill in the                             
                        art at the time the invention was made to incorporate both                                    
                        ezetimibe and fenofibrate together in a single compostion.                                    
                               One of ordinary skill in the art would have been                                       
                        motivated to incorporate both ezetimibe and fenofibrate                                       
                        together in a single composition.  The prior art teaches that both                            
                        ezetimibe and fenofibrate as useful in reducing serum                                         
                        cholesterol individually.  Therefore, combining two agents,                                   
                        which are known to be useful to reduce serum cholesterol                                      
                        individually, into a single composition useful for the same                                   
                        purpose is prima facie obvious (See In re Kerkhoven 205 USPQ                                  
                        1069).                                                                                        
                 (Answer 4.)                                                                                          
                        The burden is on the Examiner to set forth a prima facie case of                              
                 obviousness.  See In re Fine, 837 F.2d 1071, 1074, 5 USPQ2d 1596, 1598-                              


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