Appeal No. 2007-0531 Page 7 Application No. 10/341,679 The rejections based solely, or in-part, on the combination of Isner and Tischer: In our opinion the combination of Isner and Tischer fails to teach injection of an adenoviral vector comprising VEGF121 DNA directly to the internal surface of the heart. The Examiner relies on Wolff, Kovesdi, French and Ullrich to reach limitations of dependent claims. See Answer, pages 9-14. While the Examiner relies on French, the emphasis Examiner places on French is different than that set forth below. Accordingly, we vacate the pending rejections over the combination of Isner and Tischer (alone or in combination with Wolff, French, Kovesdi and Ullrich) in favor of the following new grounds of rejection. Accordingly, • the rejection of claims 1, 3, 6, 10, 19 and 22 under 35 U.S.C. § 103 as being unpatentable over the combination of Isner and Tischer is vacated; • the rejection of claims 1 and 12-18 under 35 U.S.C. § 103 as being unpatentable over the combination of Isner, Tischer and Kovesdi is vacated; • the rejection of claims 1 and 19-21 under 35 U.S.C. § 103 as being unpatentable over the combination of Isner, Tischer, Wolff and French is vacated; and • the rejection of claims 1 and 22-23 under 35 U.S.C. § 103 as being unpatentable over the combination of Isner, Tischer and Ullrich is vacated. NEW GROUNDS OF REJECTION FACTS: French teaches: 1. that in the field of cardiology, much interes has focused on developing techniques to introduce recombinant genes directlyPage: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 Next
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