Ex Parte Draaijer - Page 5

               Appeal 2007-0615                                                                           
               Application 10/204,304                                                                     

               silicone polymers (or fluorosilicone polymer in Macur) in sensors (Jolson,                 
               col. 8, ll. 53-56; Macur, col. 3, ll. 46-48, 59-60), and Lakowicz discloses                
               controlling oxygen sensitivity of the sensor by modifying the chemical                     
               composition of the substrate (i.e., silicone in Lakowicz) (Lakowicz 537).                  
               Accordingly, the prior art would have provided motivation for substituting a               
               fluorinated silicone polymer of Jolson or a fluorosilicone polymer of Macur                
               for the silicone polymer of Lakowicz.  In re Rouffet, 149 F.3d 1350, 1357,                 
               47 USPQ2d 1453, 1457-58 (Fed. Cir. 1998).                                                  
                     Moreover, we add that substitution of one known element for another                  
               known element in the field must do more than yield a predictable result.                   
               KSR Int’l Co. v. Teleflex, Inc., 127 S. Ct. 1727, 1740, 82 USPQ2d 1385,                    
               1395 (2007).  Jolson discloses using fluorinated silicone polymers in gas                  
               sensors because of their chemical inertness and high gas permeabilities                    
               (Jolson, col. 8, ll. 53-56). Moreover, Jolson indicates the interchangeability             
               of silicone polymer for fluorinated silicone polymers (Jolson, col. 8, l. 53,              
               “Silicone polymers can also be fluorinated . . . .”).  Macur uses                          
               fluorosilicone polymer in the oxygen sensor because of its oxygen                          
               permeability and ion impermeability (Macur, col. 3, ll. 46-48, 59-60).                     
               Lakowicz uses silicone because of its oxygen permeability and its barrier                  
               properties (Lakowicz 536).  In the present case, the Appellant in effect                   
               merely replaces a conventional silicone substrate with fluoridated silicone                
               polymer, each of which is known in the prior art as evinced by the                         
               disclosures of Jolson, Macur and Lakowicz.    Thus, it would have been                     
               obvious to substitute the fluorinated silicone polymer of Jolson or the                    
               fluorosilicone polymer of Macur for Lakowicz’s silicone polymer because                    
               doing so is merely the “predictable use of prior art elements according to                 

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