Ex Parte Fischer et al - Page 4


                Appeal No.  2007-0623                                                    Page 4                 
                Application No.  10/380,591                                                                     
                relative to Burgess, Vorozhtzov and Lindley2.  Instead, Appellants focus their                  
                attention on Hartmann.  Specifically, Appellants emphasize that the formula 1                   
                compounds produced by the claimed process have a hydroxyl in the R5 position,                   
                whereas Hartmann’s corresponding compound contains a methoxy in the R5                          
                position.  Brief, page 5, see also Answer, page 8.  Appellants assert that those                
                skilled in the art recognize that hydroxy and methoxy, while electronically similar,            
                are not chemically similar.  Brief, page 6.  Therefore, Appellants contend that a               
                person of ordinary skill in the art would not expect that the claimed process,                  
                which reacts a compound of formula V with an azide of formula IX, would result                  
                in a compound of formula 1.  Brief, page 4.                                                     
                       Instead, Appellants argue that “[a] skilled person would expect that the                 
                acidic phenolic group would react first with the basic azide to form [a phenolate               
                salt and] HN3 which degrades easily.”  Brief, page 6.  Appellants assert that the               
                “phenolate salt would then react in place of the azide as the nucleophile in other              
                potential reaction steps, leading to other compounds than the desired                           
                benzotriazoles.”3  Id.  Therefore, Appellants contend that “[t]here is no motivation            
                provided from the cited art to attempt such reactions in the presence of a                      
                phenol.”  Brief, page 7.                                                                        


                                                                                                                
                2 The Examiner relies on Lindley to teach a catalyst – the subject matter of claim 11.  Answer, 
                page 7.  However, since claim 11 falls together with claim 1, we do not discuss Lindley further.
                3 Appellants fail to direct our attention to any evidence on this record that supports this position.
                Attorney argument cannot take the place of evidence lacking in the record.  Meitzner v. Mindick,
                549 F.2d 775, 782, 193 USPQ 17, 22 (CCPA 1977).  We recognize Appellants’ reliance on “‘The     
                Condensed Chemical Dictionary,’ 10th Ed., 1981, Revised by Gessner G. Hawley, page 381,         
                column right, last item (diphenyl oxide).”  This reference, however, was not entered into the   
                record.  Answer, page 3.  Accordingly, we have not included this reference in our deliberations.




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