Appeal 2007-1164
Application 10/170,131
BACKGROUND
The Specification discloses “crystals of a hepatitis C virus RNA
dependent RNA polymerase called NS5B” (Specification 1). The
Specification also describes experiments in which the crystals were used to
determine the three-dimensional structure of the NS5B polymerase (pages
19-24) and the spatial coordinates of its constituent atoms (Table 1, pages
25-53).
DISCUSSION
1. CLAIMS
Claims 24 and 26 are pending and on appeal. The claims have not
been argued separately and therefore stand or fall together. 37 C.F.R.
§ 41.37(c)(1)(vii). Claim 24 is the only independent claim and reads as
follows:
24. A computer for producing a three-dimensional representation of
a molecule, wherein said molecule comprises an hepatitis C virus (HCV)
NS5B polypeptide, wherein said NS5B polypeptide comprises SEQ ID
NO: 1 with valine at position 335, alanine at position 344, and glutamine
at position 550 and is defined by structure coordinates set forth in Table
1, and wherein said computer comprises:
(a) a machine-readable data storage medium comprising a data
storage material encoded with machine-readable data, wherein
said data comprises the structure coordinates of Table 1;
(b) a working memory for storing instructions for processing
said machine-readable data;
(c) a central-processing unit coupled to said working memory
and to said machine-readable data storage medium for
processing said machine readable data into said three-
dimensional representation; and
2
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