Ex Parte Digan et al - Page 18

                Appeal 2007-1633                                                                             
                Application 09/480,236                                                                       
                in the art at the time the invention was made to substitute a PE mutant for                  
                the DT component of Neville’s immunotoxin.                                                   
                      As set forth in KSR Int’l Co. v. Teleflex Inc., 127 S. Ct. 1727, 1741-                 
                42, 82 USPQ2d 1385, 1397 (2007), “[i]n determining whether the subject                       
                matter of a patent claim is obvious, neither the particular motivation nor the               
                avowed purpose of the patentee controls.  What matters is the objective                      
                reach of the claim.  If the claim extends to what is obvious, it is invalid                  
                under § 103”; see also In re Beattie, 974 F.2d 1309, 1312, 24 USPQ2d 1040,                   
                1042 (Fed. Cir. 1992) (“[T]he law does not require that the references be                    
                combined for the reasons contemplated by the inventor.”).                                    
                      On reflection, we find no error in the Examiner’s prima facie case of                  
                obviousness.  Accordingly, we affirm the rejection of claim 35.  Claims 36-                  
                54 fall with claim 35.                                                                       

                                              CONCLUSION                                                     
                      In summary, we affirm all rejections of record.                                        















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