Ex Parte Toland - Page 9

                Appeal 2007-2681                                                                             
                Application 10/680,676                                                                       

                basis for selecting embryos is old and well known – embryos of a certain                     
                morphology tend to germinate better than others” (Answer 5).                                 
                      The Specification states that embryos “that are most likely to                         
                successfully germinate into normal plants are preferentially selected using a                
                number of visually evaluated screening criteria . . . [including] axial                      
                symmetry, cotyledon development, surface texture, [and] color” (Spec.                        
                2: 6-9).  The Specification also provides working examples of the claimed                    
                method to classify embryos according to their “morphological similarity to                   
                normal zygotic embryos” (id. at 27: 29-30) and germination rate (id. at                      
                30: 5-7).                                                                                    
                      Thus, the evidence of record appears to show that the morphological                    
                properties associated with embryos most likely to germinate into plants were                 
                well-known in the art and routinely applied by technicians in hand-sorting                   
                embryos.  In light of the state of the art and the guidance and working                      
                examples presented in the Specification, the Examiner has not adequately                     
                explained why undue experimentation would be required to use the claimed                     
                method to classify embryos according to their germination potential.                         
                      We also conclude that the Examiner has not adequately explained why                    
                the claimed method could not be practiced, without undue experimentation,                    
                using digital images of portions of embryos rather than complete embryos.                    
                As shown in the application’s Figure 1, the portions of a plant embryo                       
                include the cotyledon, hypocotyl, and radical.  Some of the morphological                    
                properties commonly used to sort embryos are those of the embryo organs                      
                (e.g., cotyledon development; Spec. 2: 8).  The Specification provides a                     
                working example of the claimed method in which the observed features used                    


                                                     9                                                       

Page:  Previous  1  2  3  4  5  6  7  8  9  10  11  12  13  Next

Last modified: September 9, 2013