Ex Parte Yoo - Page 6

                 Appeal 2007-2864                                                                                      
                 Application 10/747,798                                                                                
                 to 90% or oral cancers have been reported as having HPV DNA, and Flaitz                               
                 is cited for teaching that about one-half of oral epithelial dysplasias are                           
                 infected with HPV, and that between one-third and one-half of oral                                    
                 squamous cell carcinoma involves HPV infection (id.).  Thus, the Examiner                             
                 finds that “one of skill in the art of oral cancer would have been aware that                         
                 the treatment of Clayman would necessarily involve treatment of                                       
                 hyperplastic lesions that comprise HPV infected cells in a substantial                                
                 fraction of target patients.”  (Id.)                                                                  
                        With respect to claims 18, 33, and 54, which require that the                                  
                 composition be formulated as a douche, the Examiner asserts that “a douche                            
                 is simply a jet of liquid applied to a part of the body; so a douche solution is                      
                 simply liquid.”  (Id.)                                                                                
                        In order for a prior art reference to serve as an anticipatory reference,                      
                 it must disclose every limitation of the claimed invention, either explicitly or                      
                 inherently.  In re Schreiber, 128 F.3d 1473, 1477, 44 USPQ2d 1429, 1432                               
                 (Fed. Cir. 1997).  We find that Clayman discloses every limitation of the                             
                 claimed subject matter.  Therefore, the rejection of claims 1-12, 15, 18, 23-                         
                 28, 33, 38-48, 51 and 54 is affirmed.                                                                 
                        Appellant argues that the Examiner has not established that in                                 
                 practicing the Clayman method one is inherently practicing the claimed                                
                 invention (Br.1 5).  According to Appellant, Oda in fact teaches that a                               
                 substantial fraction of oral and cervical cancers are not infected with HPV                           
                 (id. at 6).  Appellant asserts:                                                                       


                                                                                                                      
                 1 All references to the Brief (Br.) are to the Supplemental Brief on Appeal,                          
                 dated August 23, 2006.                                                                                
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