Ex Parte Tian et al - Page 4

               Appeal 2007-3684                                                                            
               Application 10/448,794                                                                      
               skill in the relevant field to combine the elements” in the manner claimed.                 
               KSR, 127 S. Ct. at 1739, 82 USPQ2d at 1396.                                                 
                      Appellants’ principal argument is that Yu teaches away from the                      
               claimed invention.  Appellants contend that Yu teaches that enzyme                          
               catalysts cannot be used in the production of polyesters wherein lactones are               
               ring opened in the presence of hydroxyl functional unsaturated initiators.                  
               Thus, the Examiner erred in attempting to combine Yu, a reference which                     
               teaches away from the claimed invention, with other references to establish                 
               the obviousness of the claimed invention based on the disclosure of Yu. (Br.                
               12-18).                                                                                     
                      We do not find Appellants’ argument persuasive.  Yu discloses the                    
               production of polyesters wherein lactones are ring opened with a cationic                   
               ring opening catalyst in the presence of hydroxyl functional unsaturated                    
               initiators, such as hydroxyalkyl (meth)acrylates (Yu, col. 3, l. 13- col. 4, l.             
               65).  Yu differs from the claimed invention in the use of an enzyme catalyst                
               in the formation of the polyester.  Kobayashi describes a method for ring                   
               opening polymerization utilizing an enzyme catalyst (Kobayashi, col. 1, ll.                 
               7-12).  Kobayashi discloses that conventional catalysts utilized for cationic               
               reactive monomers have several drawbacks, such as side reactions and the                    
               incorporation of the catalyst into the polymer produced (Kobayashi, col. 1,                 
               ll. 25-55).  Kobayashi discloses suitable cyclic compounds for use with the                 
               catalyst to include lactones (Kobayashi, col. 3, ll. 7-10).  The Examiner cited             
               Gruning to establish that persons of ordinary skill in the art recognize that               
               enzyme catalysts are compatible with acrylate functional monomers                           
               (Answer 4).                                                                                 



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