Ex Parte RICHTER et al - Page 7

               Appeal No. 2007-3827                                                                        
               Application 08/713,905                                                                      

               the disclosure a written description of the invention defined by claim 1                    
               sufficient to establish a prima facie case, shifting the burden to Appellants to            
               establish otherwise.  Accordingly, we again evaluate all of the evidence in                 
               the written description in the Specification as a whole, giving due                         
               consideration to the weight of Appellants’ arguments in the Brief and Reply                 
               Brief.  See, e.g., In re Alton, 76 F.3d 1168, 1172, 1175-76,                                
               37 USPQ2d 1578, 1581, 1583-84 (Fed. Cir. 1996); In re Wertheim,                             
               541 F.2d 257, 262-65, 191 USPQ 90, 96-98 (CCPA 1976).                                       
                      The entire written description in the Specification must be considered               
               in determining whether the disclosure does in fact “convey with reasonable                  
               clarity to those skilled in the art that, as of the filing date sought, [Appellants         
               were] in possession of the invention . . . now claimed.”                                    
               Vas-Cath, Inc. v. Mahurkar, 935 F.2d 1555, 1563-64, 19 USPQ2d 1111,                         
               1117 (Fed. Cir. 1991); see also, e.g., In re Wilder, 736 F.2d 1516, 1520-521,               
               222 USPQ 369, 372-73 (Fed. Cir. 1984).  The determination of whether                        
               Appellants were in possession of the later claimed invention, product or                    
               process, is based on the analysis of the facts of record in each case, and is               
               not determined by any holding with respect to a certain number of species or                
               other such considerations in other product and process cases.  See, e.g.,                   
               Vas-Cath, 935 F.2d at 1561-562, 19 USPQ2d at 1116; Wertheim, 541 F.2d                       
               at 262-65, 191 USPQ at 96-98, and cases cited therein.2  Appellants can                     
               amend the originally claimed invention to avoid prior art or for other                      
                                                                                                          
               2         Broadly articulated rules are particularly inappropriate in this                  
                      area.  Mere comparison of ranges is not enough, nor are                              
                      mechanical rules a substitute for analysis of each case on its                       
                      facts to determine whether an application conveys to those                           
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