Medchem (P.R.), Inc. - Page 62




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               precautions to preserve the physical condition of the                  
               Equipment, and upon the termination of this Agreement                  
               pursuant to Section 12, shall return the Equipment to                  
               MedChem [P.R.] in good working order and in the same                   
               condition (taking into account normal wear and tear) as                
               it was initially provided to Alcon [P.R.].  In the                     
               event of any damage to the Equipment covered by                        
               insurance maintained by MedChem [P.R.], MedChem [P.R.]                 
               shall be obligated to apply any proceeds received in                   
               respect of such insurance, and Alcon [P.R.] shall be                   
               relieved from liability to the extent of such proceeds.                
                    5.  Ordering Procedure.                                           
                         5.1  Initial Annual Forecast.  MedChem [P.R.]                
               shall be responsible for directing the quantity and                    
               types of Avitene processed by Alcon [P.R.].  In that                   
               regard, MedChem [P.R.] shall, within 60 days of the                    
               date of this Agreement, deliver to Alcon [P.R.] an                     
               annual forecast (the “Initial Forecast Amount”) of                     
               MedChem[ P.R.]’s projected requirements for each                       
               Avitene product for each calendar quarter or fraction                  
               thereof during the period commencing on the date of                    
               this Agreement and ending on December 31, 1988. * * *                  
                         5.2  Subsequent Annual Forecast.  No later                   
               than August 15, 1988 and 1989, MedChem [P.R.] shall                    
               submit to Alcon [P.R.] its preliminary annual forecast                 
               of its quarterly requirements of Avitene for the next                  
               calendar year (the “Current Annual Forecast Amount”).                  
               Such preliminary annual forecast shall be updated on                   
               November 30, 1988 and 1989.                                            
                         5.3  Annual Commitment.  MedChem [P.R.] shall                
               order at least 80% of the Initial Forecast Amount or                   
               the Current Annual Forecast Amount and Alcon [P.R.]                    
               shall be required to process up to 250% of the Initial                 
               Forecast Amount or the Current Annual Forecast Amount.                 
               In this regard, Alcon [P.R.] shall be given a                          
               reasonable amount of time to meet any increases over                   
               the Initial Forecast Amount.  Alcon [P.R.] agrees, upon                
               reasonable notice, to act in good faith to meet any                    
               such increases.  In addition, in connection with                       
               MedChem[ P.R.]’s efforts to establish the MedChem                      
               [P.R.] Plant pursuant to Section 13, Alcon [P.R.]                      
               agrees, upon reasonable notice to use good faith                       
               efforts to process such reasonable amounts in excess of                
               250% of the Current Annual Forecast Amount during the                  





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