Ex parte MIZUSAWA et al. - Page 4


                 Appeal No.  1996-0906                                                                                   
                 Application No.  08/110,341                                                                             


                                                     DISCUSSION                                                          
                        In reaching our decision in this appeal, we have given careful consideration                     
                 to the appellants’ specification and claims, and to the respective positions                            
                 articulated by the appellants and the examiner.  We make reference to the                               
                 Examiner’s Answer (Paper No. 32, mailed October 2, 1995), and the Supplemental                          
                 Examiner’s Answer (Paper No. 35, mailed August 9, 1996) for the examiner’s                              
                 reasoning in support of the rejection.  We further reference appellants’ Brief (Paper                   
                 No. 30, received July 13, 1995), and appellants’ Reply Brief (Paper No. 34,                             
                 received December 4, 1995) for the appellants’ arguments in favor of patentability.                     
                 The Clark in view of Thom and Matsuo series:                                                            
                        The examiner maintains (Answer, page 5) that:                                                    
                        It would have been obvious to include lipase from Pseudomonas as                                 
                        an enzyme in the pre-spot composition of Clark for removing oil stain                            
                        from fabric or other surfaces to obtain the known function of the lipase                         
                        when used in a detergent composition or soaking liquid as disclosed                              
                        by Thom et al., i. e. [sic] the known function of lipase to hydrolyze oil                        
                        and aid in removing it from fabric.  Hydrolyzing oil with lipase would                           
                        obviously produce glycerol and fatty acids that are more soluble than                            
                        the oil and be easier to remove from fabric.  When lipase is added to                            
                        the pre-spot composition of Clark and the composition is applied to                              
                        fabric or other surface, the lipase would have obviously become                                  
                        adsorbed to the fabric or surface since Matsuo et al disclose                                    
                        adsorbing lipase to a cellulose carrier or other carriers (col 5, lines                          
                        46-50) that may be in the form of fibers (col 5, line 61).                                       
                        The initial burden of presenting a prima facie case of obviousness rests on                      
                 the examiner.  In re Oetiker, 977 F.2d 1443, 1445, 24 USPQ2d 1443, 1444 (Fed.                           
                 Cir. 1992).  In satisfying this initial burden, “it is impermissible within the framework               
                 of section 103 to pick and choose from any one reference only so much of it as will                     

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