Ex parte MIZUSAWA et al. - Page 7


                 Appeal No.  1996-0906                                                                                   
                 Application No.  08/110,341                                                                             


                 supra, the object of Thom’s invention is to avoid the very step the examiner cites                      
                 Thom as suggesting.                                                                                     
                        With regard to Matsuo, appellant argues (Brief, page 15) that “the mere                          
                 showing that lipase is adsorbed to cellulose, which the Examiner attributes to                          

                 Matsuo et al., does not remedy the significant failings and incompatibilities … of the                  

                 Clark and Thom et al. references.”                                                                      

                        Before a conclusion of obviousness may be made based on a combination                            
                 of references, there must have been a reason, suggestion or motivation to lead an                       
                 inventor to combine those references.  Pro-Mold and Tool Co. v. Great Lakes                             

                 Plastics Inc., 75 F.3d 1568, 1573, 37 USPQ2d 1626, 1629 (Fed. Cir. 1996).  When                         

                 identifying the motivation required to combine references the examiner is not free to                   
                 pick and choose from any one reference only so much of it as will support a given                       
                 position to the exclusion of other parts.  Wesslau, 353 F.2d at 241, 147 USPQ at                        
                 393; see also Mercer, 515 F.2d at 1165-66, 185 USPQ at 778.                                             
                        On these facts, we find that the only reason or suggestion to modify the                         
                 references to arrive at the present invention comes from appellants’ specification.                     
                 Contrary to the examiner’s position, while Thom references as background a prior                        
                 art teaching of a lipase liquor for use in a soaking step, the objective of Thom’s                      
                 invention was to avoid this cumbersome wash process that is of limited applicability                    
                 in practice.                                                                                            





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