Ex parte MIZUSAWA et al. - Page 10


                 Appeal No.  1996-0906                                                                                   
                 Application No.  08/110,341                                                                             


                        In response to appellants’ argument, the examiner states                                         
                 (Supplemental Answer, bridging paragraph, pages 6-7) that:                                              
                        [T]he rejection is not based on combining the self-cleaning cloth [of                            
                        Butler] with the detergent of Thom et al but on using as the enzyme of                           
                        Butler that cleans a soiled butcher’s apron, the lipase from                                     
                        Pseudomonas disclosed by Thom et al. … The apron contains                                        
                        attached enzymes such as lipase that … remove the oil or fat without                             
                        the presence of a detergent.                                                                     
                        Appellants  address (Reply Brief, page 7) this detergent aspect by                               
                 referencing column 2, lines 16-24 of Thom (discussed above) stating that                                
                 “Thom et al.’s detergent wash composition for washing fabrics teaches away                              
                 from the non-detergent pre-wash preparation of a ‘self-cleaning’ derivatized                            
                 cloth such as that of Butler which … loses its ‘self-cleaning’ properties in the                        
                 presence of a detergent wash composition.”  Appellants emphasize (Reply                                 
                 Brief, page 7) that “prior art references are to be considered as a whole, and                          
                 portions arguing against or teaching away from the claimed invention must                               
                 be considered.”                                                                                         
                        In response, the examiner states (Supplemental Answer, page 7) “[i]t                             
                 is granted … that the references as a whole must be considered.  This is the                            
                 reason that one must consider the entire teachings of Thom et al including                              
                 the teaching that it is known in the prior art to use lipase in a soaking step                          
                 followed by a washing step with a detergent-containing liquor.”  The examiner                           
                 again ignores the disclosure in Thom (column 1, lines 45-49) which                                      
                 specifically states “these specifications [which refer to the section relied                            


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