Ex parte MIZUSAWA et al. - Page 11


                 Appeal No.  1996-0906                                                                                   
                 Application No.  08/110,341                                                                             


                 upon by the examiner] needed two separate formulated products; it was                                   
                 cumbersome and it would be of limited applicability in practice.”  The                                  
                 examiner also ignores Thom’s objective (column 2, lines 4-24) of avoiding                               
                 exactly what the examiner relies upon Thom as teaching.                                                 
                        Appellants argue (Reply Brief, page 9) that ”[t]he examiner has                                  
                 impermissibly relied on the Appellants’ own disclosure to piece together                                
                 claimed elements and to combine them as claimed, without any teaching or                                
                 suggestion of and in the fact of numerous teachings away from, doing so.”  In                           
                 addition appellants argue (Reply Brief, page 9) that the “Matsuo                                        
                 et al. transesterification method does not make up for the deficiencies of the                          
                 underlying combination.”                                                                                
                        We emphasize that before a conclusion of obviousness may be made based                           
                 on a combination of references, there must have been a reason, suggestion or                            
                 motivation to lead an inventor to combine those references.     Pro-Mold and Tool                       
                 Co. v. Great Lakes Plastics Inc., 75 F.3d at 1573,                37 USPQ2d at 1629.                    
                 On these facts, we agree with appellants that the only reason or suggestion to                          
                 modify the references to arrive at the present invention comes from appellants’                         
                 specification.  Contrary to the examiner’s position, while Thom references as                           
                 background a prior art teaching of a lipase liquor for use in a soaking step, the                       
                 objective of Thom’s invention was to avoid this cumbersome process that is of                           
                 limited applicability in practice.                                                                      



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