Appeal No. 95-0777 Application 07/756,411 render obvious a method for making the claimed compounds. As stated by the court in In re Hoeksema : 3 Thus, upon careful reconsideration it is our view that if the prior art of record fails to disclose or render obvious a method for making a claimed compound, at the time the invention was made, it may not be legally concluded that the compound itself is in the possession of the public [footnote omitted]. In this context, we say that the absence of a known or obvious process for making the claimed compounds overcomes a presumption that the compounds are obvious, based on close relationships between their structures and those of prior art compounds. See also In re Payne, 606 F.2d 303, 314-15, 203 USPQ 245, 255 (CCPA 1979), and In re Brown, 329 F.2d 1006, 1011, 141 USPQ 245, 249 (CCPA 1964). References relied upon to support a rejection under 35 U.S.C. § 103 must provide an enabling disclosure, i.e., they must place the claimed invention in the possession of the public. In re Payne, 606 F.2d at 314, 203 USPQ at 255. Appellants argue that there is no known way to make the substitution proposed by the examiner (brief, page 7). Appellants cite evidence from Carter II and U.S. Patent No. 5,077,277 (of record) that the proposed methods of preparing the claimed compounds, as suggested by the examiner, would not result in the claimed compounds (see page 8 of the brief). 3399 F.2d 269, 274, 158 USPQ 596, 601 (CCPA 1968). 4Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 NextLast modified: November 3, 2007