Appeal No. 97-3097
Application 08/030,488
APPENDIX
1. In a method of monitoring the growth of micro-
organisms in liquid culture in a gas-tight container
incorporating a flexible diaphragm capable of moving in
response to pressure changes within the container, by
detecting displacement of the diaphragm, the improvement
wherein the position or confirmation of the diaphragm is
repeatedly sensed using a laser as distance-measuring means,
and wherein a portion of the container adjacent the diaphragm
is used as a reference against which all relative positional
or conformational changes of the diaphragm are detected, said
diaphragm being capable of moving between concave and convex
configurations in response to pressure changes within the
container.
12. Apparatus for monitoring the growth of micro-
organisms in liquid culture, comprising
means for holding an array of gas-tight containers each
containing a liquid test sample and each incorporating a
flexible diaphragm capable of moving in response to pressure
changes within the container,
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