Appeal No. 95-0334 Application 08/002,513 in yields comparable to prior art methods wherein diacetone-2- keto-L-gulonic acid (DAGA) is used as the starting material. Appealed claims 1 and 3-6 stand rejected under 35 U.S.C. § 103 as being unpatentable over Fujiwara in view of Bassford and Japanese '217. Upon thorough review of the opposing arguments presented by appellants and the examiner, we concur with appellants that the examiner has failed to establish a prima facie case of obviousness for the claimed subject matter. Accordingly, we will not sustain the examiner's rejection. The examiner recognizes that Fujiwara discloses making L-ascorbic acid from either DAGA or GA, but without an aliphatic ketone being present in the starting reaction medium. To remedy this deficiency in Fujiwara, the examiner relies upon the disclosures of Bassford and Japanese '217. Bassford teaches that when L-ascorbic acid is prepared from DAGA, a ketone, such as acetone, is liberated and dissolves in the solvent layer, thereby facilitating its removal from the reaction medium. Japanese '217 incorporates acetone in a reaction medium comprising DAGA to dissolve intermediate ester compounds. Based on the disclosures of Bassford and Japanese '217, the examiner concludes that it would have been obvious -3-Page: Previous 1 2 3 4 5 6 7 NextLast modified: November 3, 2007