Appeal No. 95-0976 Application No. 07/936,558 BACKGROUND Claims 1-12 are drawn to compounds which are derivatives of known cyclohexapeptidyl compounds. These compounds are known in the art as echinocandins. Claims 13 and 14 are drawn to antibiotic compositions comprising the compounds of claim 1. The compounds that were starting materials for the production of the claimed compounds are echinocandin hexapeptidyl compounds extracted from microbial fermentates. These parent compounds and their antibiotic activity were known prior to the filing date of this application. DISCUSSION Rejection based on 35 U.S.C. § 112 Claim 1 stands rejected under 35 U.S.C. § 112, first paragraph, as having been based on a non-enabling disclosure. Although phrased various ways the position of the examiner is that the single in vivo example of the claimed antibiotic activity is inadequate to provide the necessary guidance to one of skill in the art to practice the invention across the scope of the claim. The claims at issue encompass 9Page: Previous 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 NextLast modified: November 3, 2007