Appeal No. 95-0976 Application No. 07/936,558 Appellants argue that the requirement of the claimed compounds and compositions with respect to the propanolamine substituent at the Thr position is neither taught nor suggested by the applied art. We agree with appellants in this regard. This position being dispositive of the issue of obviousness for each of the claims we will not reach the other questions raised by appellants. We note in particular the issue as to the claimed R position desmethyl variations (set5 forth in claims 2-12 herein) and point out that the Supplemental Examiner's Answer (Paper #17) refers to variations of echinocandins obtained from a particular microbial source. However, appellants did not file any Reply Brief to address this reasoning. We take no position on this specific matter. The examiner bears an initial burden of establishing that one of ordinary skill in the art would have found the claimed invention to have been obvious at the time that it was made. The evidence relied upon must support such a conclusion. As was set forth in In re Vaeck, 947 F.2d 488, 493, 20 USPQ2d 1438, 1442 (Fed. Cir. 1991): Where claimed subject matter has been rejected 15Page: Previous 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NextLast modified: November 3, 2007