Ex parte GRIEVES et al. - Page 4




          Appeal No. 95-2204                                                          
          Application 08/018,356                                                      


          that is to say, a similarity in chemical structure and function             
          between a prior art compound and a claimed compound, whereby one            
          skilled in the art would have been motivated to make a claimed              
          compound in the expectation that compounds similar in structure             
          will have similar properties.  In re Payne, 606 F.2d 303, 313,              
          203 USPQ 245, 254 (CCPA 1979).  In essence, therefore, the                  
          examiner would argue that the diamines of claim 32 are so similar           
          in structure to those of von Bramer that the artisan would have             
          been motivated to make and use such claimed diamines as primers             
          expecting them to possess the primer function exhibited by                  
          patentee’s diamines.                                                        
               On the record before us, however, the examiner has advanced            
          no support for the proposition that appellants’ claimed and von             
          Bramer’s disclosed diamines and in particular the ethane versus             
          1,3-butane substituents thereof are sufficiently similar in                 
          chemical structure whereby the artisan would have expected the              
          1,3-butane-containing diamine to possess the primer                         
          characteristics of patentee’s ethane-containing diamine.                    
          Moreover, our own research in this matter has failed to reveal              
          any support for such a proposition.  Under these circumstances,             
          any structural similarity that may exist between the respective             
          diamines of claim 32 and of von Bramer is inadequate to establish           

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