Appeal No. 95-2603
Application 07/915,871
Again the examiner has not specifically pointed out where this
teaching occurs in Williams. Williams discloses tricyclic
hetero compounds containing nitrogen and oxygen with amino
acid substituents useful in the treatment of Herpes simplex
virus. No disclosure can be found of the bicyclam compounds
of the appealed claims.
For the foregoing reasons, this rejection under § 103 is
reversed.
C. The Rejection under § 103 over Ciampolini and Lehn in
view of Kimura
This new ground of rejection is actually two grounds of
rejection. Ciampolini is applied alone with no secondary
reference but Lehn is modified by Kimura (see the answer,
pages 8-9). This rejection will be discussed accordingly.
Lehn has been discussed above. Kimura, which allegedly
teaches the bridging of two macrocyclic polyamine complexes
into the claimed bis compounds, is applied to provide guidance
on how this chemical “configuration” would affect the
biological systems of interest (answer, page 9). However,
Kimura is not related to biological systems and the examiner
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