Ex parte PICARD et al. - Page 8




          Appeal No. 95-2879                                                          
          Application 08/085,657                                                      



          the issue of homologs and structural similarity between the                 
          referenced groups has not been raised by the examiner.                      
          Rather,                                                                     
          on this record, we find only assertions and allegations by the              
          examiner that the McLamore reference suggests that alkyl and                
          phenyl (substituted or unsubstituted) groups are equivalent.                
          See, e.g., Answer, sentence bridging pp. 6-7.  The examiner                 
          has not pointed to any teachings within the patent which                    
          support his position or provide any explanation as to why                   
          these groups are so similar that it would have been obvious to              
          those of ordinary skill in the art to substitute one for the                
          other in order to arrive at the claimed invention.  In                      
          addition, we find that the examiner has overlooked the fact                 
          that the references must also suggest that the combination of               
          a substituted phenyl and an aliphatic group will result in the              
          compound which is capable of lowering blood sugar levels.2                  


               We note the appellants’ arguments throughout the main Brief and Reply2                                                                     
          Brief that the instant compounds are for reducing cholesterol and, not for  
          reducing blood sugar.  We find such arguments to be misguided.  It is well  
          established that the motivation to combine references does not have to be   
          identical to that of the patent applicant in order to establish a prima facie
          case of obviousness.  In re Kemps, 97 F.3d 1427, 1430, 40 USPQ2d 1309, 1311 
          (Fed. Cir. 1996).                                                           
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