Appeal No. 95-4721 Application No. 08/128,332 would have been obvious to one of ordinary skill in the art within the meaning of § 103 in view of the applied prior art. Accordingly, we will sustain the examiner's rejection. We have little doubt that one of ordinary skill in the art, armed with the disclosure of Dix, would have found appellants' claimed process prima facie obvious. As explained by the examiner, Dix evidences that it was known in the art to perform an amination process on aryl halides by reacting a secondary amine with an aryl halide in the presence of N- methylpyrrolidone as a solvent, which solvent is within the scope of appealed claim 11 and specifically recited in dependent claim 7. Dix teaches that N-methylpyrrolidone is a preferred solvent (column 1, line 62). Dix also teaches that bromine is a preferred halogen substituent on the aryl group (column 2, line 12). In addition, the reference teaches that a preferred temperature range for the reaction is 100 to about 280EC (column 2, line 27), which range totally embraces, and is almost congruent with, the claimed range of 100E to 220EC. Like appellants' process, the process disclosed by Dix provides an improved yield of aryl amine when the aryl halide is directly aminated -4-Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 NextLast modified: November 3, 2007