Ex parte ROCHAT et al. - Page 4




          Appeal No. 95-4721                                                          
          Application No. 08/128,332                                                  


          would have been obvious to one of ordinary skill in the art                 
          within the meaning of § 103 in view of the applied prior art.               
          Accordingly, we will sustain the examiner's rejection.                      
               We have little doubt that one of ordinary skill in the                 
          art, armed with the disclosure of Dix, would have found                     
          appellants' claimed process prima facie obvious.  As explained              
          by the examiner, Dix evidences that it was known in the art to              
          perform an amination process on aryl halides by reacting a                  
          secondary amine with an aryl halide in the presence of N-                   
          methylpyrrolidone as a solvent, which solvent is within the                 
          scope of appealed claim 11 and specifically recited in                      
          dependent claim 7.  Dix teaches that N-methylpyrrolidone is a               
          preferred solvent (column 1,                                                
          line 62).  Dix also teaches that bromine is a preferred                     
          halogen substituent on the aryl group (column 2, line 12).  In              
          addition, the reference teaches that a preferred temperature                
          range for the reaction is 100 to about 280EC (column 2, line                
          27), which range totally embraces, and is almost congruent                  
          with, the claimed range of 100E to 220EC.  Like appellants'                 
          process, the process disclosed by Dix provides an improved                  
          yield of aryl amine when the aryl halide is directly aminated               

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