Appeal No. 95-5067 Application 08/064,575 salt “attacks the activated fluorine-carbon bond of the diphenyl sulfone” (Kricheldorf ‘83, page 2286). The fluorine of Kricheldorf ‘83 and ‘84 is attached to an aromatic ring. There is no disclosure, teaching or suggestion, in the record before us, that the cesium alkoxide or phenolate would attack the vinylic fluoride reactant of the primary references. Accordingly, we find no suggestion or motivation to combine the primary and secondary references in the manner suggested by the examiner. The Saunders secondary reference differs from Kricheldorf ‘83 and ‘84 in disclosing the reaction of a silyl ether with alkyl halide to form alkyl aryl ethers (page 377). As noted above, we find no suggestion or motivation to apply the teachings of Saunders to the reaction of alcohols with the vinylic fluorides of the primary references. Furthermore, appellants have submitted Morrison to show that “attempts to convert aryl or vinyl halides into ... ethers... by treatment with the usual nucleophilic reagents are also unsuccessful” (sentence bridging pages 823-24). For the foregoing reasons, we conclude that the examiner has failed to establish a prima facie case of obviousness for 7Page: Previous 1 2 3 4 5 6 7 8 9 NextLast modified: November 3, 2007