Appeal No. 96-0009 Application 08/104,417 § 112, first paragraph, see In re Brana, 51 F.3d 1560, 1564 n. 12, 34 USPQ2d 1436, 1439 n.12 (Fed. Cir. 1995); In re Jolles, 628 F.2d 1322, 1326 n.10, 206 USPQ 885, 889 n.11 (CCPA 1980); In re Fouche, 439 F.2d 1237, 1243, 169 USPQ 429, 434 (CCPA 1971), we address both the issues of utility and enablement. Appellants point out that the claimed invention is directed toward a method for inhibiting the L-glutamate neurotransport system and not toward a method for treating disorders of central nervous systems in humans, and argue that in their method, as stated in their specification (page 5, lines 6-14), specific inhibitors of L-glutamate uptake provide useful probes for evaluating the role of the transport system in neurotransmission (brief, pages 15 and 18). As evidence that the claimed invention has the asserted utility, appellants rely upon their specification, the second declaration of Dr. Richard Bridges, filed on March 14, 1994, and an advertisement newsletter by the British company Tocris Neuramin.2 2 The Tocris Neuramin advertisement newsletter states that L-trans-pyrrolidine-2,4-dicarboxylic acid inhibits L-glutamate uptake into synaptosomes, but provides no supporting data. 4Page: Previous 1 2 3 4 5 6 7 8 9 NextLast modified: November 3, 2007