Ex parte SKOLNICK et al. - Page 10




          Appeal No. 97-1999                                                          
          Application 07/390,745                                                      
          explain why Marvizon may not be considered prior art under §                
          102(a).                                                                     
               A Declaration under 37 CFR § 1.131 by Skolnick, Lewin,                 
          Marvizon, Monn, and Rice filed on March 20, 1995 (Paper No.                 
          31) reads on page 2, paragraphs 3 and 4, thereof:                           
                    3.   At least as early as November 15, 1988, ethyl                
               and methyl esters of ACPC were conceived, synthesized and              
               tested for activity by three of us, Phil Skolnick, James               
               Monn, and Kenner Rice, prior to publication of the                     
               Marvisón [sic, Marvizón], et al., and Nadler, et al.                   
                    publications, as demonstrated by Attachment A.                    
          Attachment A are notebook pages, from the laboratory manual                 
          of Barrington       Jackson, a student who conducted research               
          in Dr. Skolnick’s laboratory at his direction and under his                 
          supervision, with dates marked out.                                         
                    4.   At least as early as November 15, 1988, ACPC had             
               been conceived, obtained and tested for binding to the                 
               glycine site of the NMDA receptor, by Phil Skolnick,                   
               Anita Lewin, and Juan-Carlos Marvizon, as demonstrated by              
               Attachment B.  Attachment B are pages from the laboratory              
               manual of Dr. Marvisón [sic, Marvizón], with the dates                 
               marked out.                                                            
          The declarants support the above statements with Attachments A              
          and B which appear to be copies of laboratory notebook pages                
          and a computer-originated data sheet.  The purpose, content,                
          and meaning of the information in the attached laboratory                   
          notebook pages and data sheets are unclear from the attached                
          papers themselves.  Moreover, the declarants proffer no                     
          further explanation of that information in the text of the                  

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