Ex parte KLOSE - Page 6




          Appeal No. 95-2441                                                          
          Application 07/987,211                                                      
          in treating hyperlipoproteinemia in humans reasonably would                 
          have suggested the use of the same type of delivery system for              
          treating or feeding ruminants gemfibrozil or bioactive                      
          substances recognized in the art for use in treating or                     
          feeding ruminants to persons having ordinary skill in the art.              
          We find that G-S encapsulates gemfibrozil with a hydrophobic                
          coating in order to avoid the particularly unpleasant after-                
          taste humans associate with gemfibrozil (G-S, col. 2, l. 17-                
          21).  The examiner has not explained why persons having                     
          ordinary skill in the art would have been led by G-S’s                      
          teaching to employ the same or a similar means to deliver                   
          bioactive feed supplements or any other treating agent to                   
          ruminants.  The examiner’s rejection appears to be based on                 
          impermissible hindsight.                                                    




          2.   Rejection in view of Sibbald, Iijima, UK, and Hawley                   
               We find, as did the examiner (Ans., p. 4, first full                   
          para.), that Sibbald describes compositions comprising                      
          bioactive material totally encapsulated with a hydrophobic                  
          coating.  The compositions are expressly designed to transport              
          the bioactive material through the rumen of a ruminant.  The                
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