Ex parte JAYASENA et al. - Page 6




                  Appeal No. 1995-2611                                                                                                                    
                  Application 07/808,452                                                                                                                  



                  cleaving of RNA encoding HIV proteins is benificial [sic] to the prevention of viral                                                    
                  replication."  By this statement, we assume the examiner believes that the four references,                                             
                  relied upon,  teach or suggest to one of ordinary skill in the art to make the  claimed                                                 
                  modified viral peptide with the expectation that it would work in vivo to prevent viral                                                 
                  replication.  However, the examiner has not pointed to any disclosure in the references in                                              
                  support of this conclusion.  We remind the examiner that a conclusion of obviousness must                                               
                  be based upon facts, not generalities.  In re Warner, 379 F.2d 1011, 1017, 154 USPQ                                                     
                  173, 178   (CCPA 1967), cert. denied, 389 U.S. 1057 (1968);  In re Freed, 425 F.2d 785,                                                 
                  788, 165 USPQ 570, 571 (CCPA 1970).   Absent a more fact-based explanation from the                                                     
                  examiner as to why the four references relied upon would have rendered the subject matter                                               
                  claimed obvious to one of ordinary skill in the art, we must reverse the rejection.                                                     
                           The decision of the examiner is reversed.                                                                                      
                                                                    REVERSED                                                                              
                                                                                                   )                                                      
                                                      William F. Smith                             )                                                      
                                                      Administrative Patent Judge                  )                                                      
                                                                                                   )                                                      
                                                                                                   )                                                      
                                                                                                   ) BOARD OF PATENT                                      
                                                      Joan Ellis                                   )                                                      
                                                      Administrative Patent Judge                  )   APPEALS AND                                        
                                                                                                   )                                                      
                                                                                                   ) INTERFERENCES                                        
                                                                                                   )                                                      

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