Appeal No. 1995-3047
Application No. 07/805,729
15. A highly water-soluble, stable, crystalline salt of 2',3'-dideoxy-2'-fluoroinosine of
Formula (III):
wherein X is an alkali or alkaline earth metal ion, an ammonium ion or a quaternary amino
ion, and n is 0.5 to 2.0.
The references relied on by the examiner are:
Verheyden et al. (Verheyden) 3,817,982 Jun. 18, 1974
Mitsuya et al. (Mitsuya) WO 87/01284 Mar. 12, 1987
Marquez et al. (Marquez) 0 287 313 Oct. 19, 1988
(European Patent Application)
Lin et al. 0 273 277 Jul. 06, 1988
(European Patent Application)
Lin et al., "Potent and Selective in Vitro Activity of 3'-Deoxythymidin-2'-ene
(3'-Deoxy-2',3'-didehydrothymidine) Against Human Immunodeficiency
Virus," Biochemical Pharmacology, vol. 36 no. 17, pgs. 2713-2718 (1987).
(Lin)
3
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