Appeal No. 1995-3047
Application No. 07/805,729
Hamamoto et al. "Inhibitory Effect of 2',3-Didehydro-2',3'-Dideoxynucleo-
sides on Infectivity, Cytopathic Effects, and Replication of Human
Immunodeficiency Virus," Antimicrobial Agents and Chemotherapy, vol. 31,
no. 6, pgs. 907-910 (1987). (Hamamoto)
Baba et al.(I), "Ribavirin Antagonizes Inhibitory Effects of Pyrimidine
Dideoxynucleosides but Enhances Inhibitory Effects of Purine 2',3'-
Dideoxynucleosides on Replication of Human Immunodeficiency Virus In
Vitro,"Antimicrobial Agents and Chemotherapy vol. 31, no. 10, 1613-1617
(1987). (Baba(I))
Baba et al. (II), "Both 2',3'-Dideoxythymidine and its 2',3-Unsaturated
Derivative (2',3'-Dideoxythymidinene) Are Potent and Selective Inhibitors of
Human Immunodeficiency Virus Replication In Vitro," Biochemical
Biophysical Research Communications., vol. 142, no. 1, pgs. 128-134
(1987). (Baba(II)
Balzarini et al., "Estimation of the Lipophilicity of Anti-HIV Nucleoside
Analogues by Determination of the Partition Coefficient and Retention Time
on a Lichrospher 60 RP-8 HPLC Column," Biochemical and Biophysical
Research Communications., vol. 158, no. 2, pgs. 413-422 (January 1989).
(Balzarini)
DeClercq, "Potential Drugs for the Treatment of AIDS," J. Antimicrobial
Chemotherapy, Suppl. A, 23, pgs. 35-46 (1989).
In the answer, page 4, the examiner states that U.S Patent No. 4,861,759, issued
August 29, 1989 to Mitsuya et al., is "equivalent" to International Publication No. WO
87/01284. Likewise, the examiner states that U.S. Patent No. 4,978,655, issued
December 18, 1990 to Lin et al., is "equivalent" to the above-cited Lin et al.
4
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