Appeal No. 95-3746
Application 08/063,431
claims 1-16, which are all of the claims in the application.
THE INVENTION
Appellants claim methods for treating mammals to
selectively block the uptake of serotonin (5-HT) and dopamine
by administering to the mammals tropane derivatives having a
recited formula. Claim 1 is
illustrative and reads as follows:
1. A method of treating
mammals to selectively block
5-HT uptake, said method comprising:
administering a small but
effective amount of a 3-aryltropane derivative of the formula:
and structural isomers thereof,
wherein R is an aromatic ring moiety selected from the
1
group consisting of 1-naphthyl, 1-naphthyl, phenyl, C to C1 8
alkylaryl, and indole; and
R and R may be the same or different and are selected2 3
from the group consisting of hydrogen, C to C ketones, and1 8
R is methyl, hydrogen or lower alkyl.
4
2
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