Ex parte MERUELO et al. - Page 5




          Appeal No. 95-4441                                                          
          Application No. 07/970,229                                                  


               We refer to the Brief and Reply Brief and to the Answer                
          for a complete exposition of the opposing viewpoints expressed              
          by the appellants and the examiner concerning the above noted               
          rejections.                                                                 
                                       OPINION                                        
               For the reasons set forth below, we will sustain the                   
          examiner’s prior art rejection of claims 13 through 15, 18                  
          through 23, 26 and 27 but not the prior art rejection of                    
          claims 17 and 25.                                                           
               As acknowledged by the appellants and as evinced by, for               
          example, the Brockmann and Lavie references, hypericin was                  
          known in the prior art to possess antiviral activity.  In our               
          view, the compounds defined by claims 14 and 22 and by claims               
          15 and 23 are so similar in structure to hypericin that one                 
          having an ordinary level of skill in the art would have                     
          modified the latter to obtain the former based upon a                       
          reasonable expectation of obtaining compounds which, like                   
          hypericin, possess antiviral activity.  This conclusion of                  
          obviousness is based upon the theory that compounds similar in              
          structure will have similar properties as explained, for                    


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