Ex parte CHANG et al. - Page 9




          Appeal No. 95-4491                                                          
          Application No. 07/864,210                                                  


               of the instant invention would have been motivate                      
               [sic, motivated] to combine hyaluronic acid and                        
               chondroitin sulfate and to use the resulting                           
               composition for the protection of eyes.  The above                     
               rejection is based on the well established                             
               proposition of patent law that no patentable                           
               invention resides in combining old ingredients of                      
               known properties where the results obtained thereby                    
               are no more than the additive affects [sic, effects]                   
               of the ingredients.                                                    
               We disagree with appellants that the references, namely                
          Healon and Drugs in Japan, disclose different utilities, and                
          therefore, were not properly combined.  In contrast to                      
          In re Geiger, 815 F.2d 686, 2 USPQ2d 1276 (Fed. Cir. 1987),                 
          the teachings in Healon and Drugs in Japan provide a                        
          suggestion supporting their combination.  Both references                   
          disclose that their compositions protect corneal tissue from                
          injury.  See     In re Kerkhoven, 626 F.2d 846, 850, 205 USPQ               
          1069, 1072 (CCPA 1980) (“[i]t is prima facie obvious to                     
          combine two compositions each of which is taught by the prior               
          art to be useful for the same purpose, in order to form a                   
          third composition which is to be used for the very same                     
          purpose").  Furthermore, there is no reason to believe that                 
          resulting injury to corneal tissue during surgery differs from              
          injury to corneal tissue caused by other trauma.  See                       

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