Ex parte NISHIOKA et al. - Page 4




              Appeal No. 1995-4623                                                                                         
              Application No. 07/918,588                                                                                   


              the only reason, suggestion, or motivation to arrive at those cyclized pentapeptides stems                   
              from appellants' specification and not from the cited prior art.  It follows, in our judgment,               
              that the rejections under 35 U.S.C. § 103 are based on the impermissible use of hindsight                    
              and cannot stand.  The rejections under 35 U.S.C. § 103 are reversed.                                        
                                                    SECTION 102(f)                                                         

                     Claims 1 through 3 stand rejected because, according to the examiner, applicants                      
              themselves did not invent the subject matter sought to be patented.            35 U.S.C. §                   
              102(f).  In setting forth this rejection, the examiner (1) cites the O'Connor publication                    
              entitled "Quenched Molecular Dynamics Simulations of Tuftsin and Proposed Cyclic                             

              Analogues"; and (2) refers to O'Connor's description of ctuf  (cyclo[Thr-Lys-Pro-Arg-Gly])                   
                                                                             2                                             
              at page 2878 second column and ctuf  (cyclo[Thr-Lys-Pro-Arg-Asp]) at page 2879 second                        
                                                      4                                                                    
              column.  According to the examiner, the peptides recited in claims 1 through 3 are                           
              identically described in the O'Connor publication which is co-authored by two of the                         
              present inventors (Fahad Al-Obeidi and Montgomery Pettitt) and two others.  The examiner                     
              argues that this set of                                                                                      
              facts "raises a question of inventorship" and that, in the absence of a satisfactory showing,                
              it is unclear whether "the inventorship of the application has been properly                                 





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