Ex parte DAVIS et al. - Page 10




          Appeal No. 95-4692                                                          
          Application 08/141,316                                                      


          Inc., 776 F.2d 281, 297 n. 24, 227 USPQ 657, 667 n. 24 (Fed.                
          Cir. 1985), cert. denied, 475 U.S. 1017 (1986).  It is                      
          impermissible for the examiner to use the applicants'                       
          specification as an instruction manual or template to piece                 
          together the teachings of the prior                                         
          art.  In re Dow Chemical Co., 837 F.2d 469, 473, 5 USPQ2d                   
          1529, 1531-32 (Fed. Cir. 1988).                                             
               In the case before us, the examiner’s overall position is              
          that since one of ordinary skill in the art routinely                       
          synthesizes pravastatin by contacting certain genera of                     
          microorganisms  with compactin, esters or salts thereof, it,3                                                             
          therefore, would have been obvious to such persons to produce               
          pravastatin by contacting any genera of microorganism with                  
          compactin, or analogs thereof.  However, from a fair reading                
          of the references relied upon by the examiner, it is difficult              
          for us to discern on what basis this conclusion was reached.                
               In our view, the teachings of the Terahara patents are                 



               Viz., Mucor, Rhizopus, Zygorynchus, Circinella,3                                                                     
          Actinomucor, Gongronella, Phycomyces, Martierella, Pycnoporus,              
          Rhizoctonia, Absidia, Cunninghamella, Syncephalastrum,                      
          Streptomyces and Nocardia.                                                  
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