Appeal No. 95-4692 Application 08/141,316 Inc., 776 F.2d 281, 297 n. 24, 227 USPQ 657, 667 n. 24 (Fed. Cir. 1985), cert. denied, 475 U.S. 1017 (1986). It is impermissible for the examiner to use the applicants' specification as an instruction manual or template to piece together the teachings of the prior art. In re Dow Chemical Co., 837 F.2d 469, 473, 5 USPQ2d 1529, 1531-32 (Fed. Cir. 1988). In the case before us, the examiner’s overall position is that since one of ordinary skill in the art routinely synthesizes pravastatin by contacting certain genera of microorganisms with compactin, esters or salts thereof, it,3 therefore, would have been obvious to such persons to produce pravastatin by contacting any genera of microorganism with compactin, or analogs thereof. However, from a fair reading of the references relied upon by the examiner, it is difficult for us to discern on what basis this conclusion was reached. In our view, the teachings of the Terahara patents are Viz., Mucor, Rhizopus, Zygorynchus, Circinella,3 Actinomucor, Gongronella, Phycomyces, Martierella, Pycnoporus, Rhizoctonia, Absidia, Cunninghamella, Syncephalastrum, Streptomyces and Nocardia. 10Page: Previous 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 NextLast modified: November 3, 2007