Ex parte DAVIS et al. - Page 11




          Appeal No. 95-4692                                                          
          Application 08/141,316                                                      


          directed to the use of specific genera of microorganisms and                
          specific substrates.  We do not find, nor has the examiner                  
          pointed out, any teachings in the Terahara patents which would              
          have suggested to those of ordinary skill in the art, the use               
          of the claimed genera of microorganisms to produce pravastatin              
          from compactin or the claimed analogs.  On this record, the                 
          only place we find such a suggestion is in the appellants’                  
          specification.  Thus, in our view, the examiner has relied on               
          impermissible “hindsight” to arrive at the conclusion that the              
          present invention is obvious over the prior art.  In re                     
          Fritch, supra; Interconnect Planning Corp. v. Feil, 774 F.2d                
          1132, 1138, 227 USPQ 543, 547 (Fed. Cir. 1985) (“It is                      
          impermissible to engage in hindsight reconstruction of the                  
          claimed invention, using the applicant’s structure as a                     
          template and selecting elements from references to fill the                 
          gaps”).                                                                     
               Accordingly, the rejection is reversed.                                
                                    Other Issues                                      
               Upon return of this application to the corps, the                      
          examiner should reconsider whether there is a factual basis                 


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