Ex parte MAJARIAN et al. - Page 4




                 Appeal No. 95-4700                                                                                                              
                 Application 07/837,668                                                                                                          

                         We affirm the prior art rejections and reverse the rejection under 35 U.S.C.                                            
                 § 112, second paragraph.                                                                                                        
                                                               DISCUSSION                                                                        
                 1. Prior art rejections                                                                                                         
                         In reviewing the “Replacement Brief on Appeal” (Paper No. 37, August 26, 1994)                                          
                 we note that appellants do not substantively argue the merits of the rejections under                                           
                 35 U.S.C. § 103.  Rather, appellants rely upon the arguments presented in regard to the                                         
                 anticipation rejection premised upon Asaka in support of the patentability of the claims                                        
                 rejected under 35 U.S.C. § 103.  See page 4 of this paper.  Furthermore, in regard to the                                       
                 rejection under 35 U.S.C. § 102(e), appellants have stated that “the claims can be grouped                                      
                 together.”  See page 3 of this paper.  Accordingly, the dispositive question in regard to the                                   
                 prior art rejections pending in this appeal is whether Asaka describes a recombinant gene                                       
                 as required by claim 1 on appeal?                                                                                               
                 We answer this question in the affirmative.                                                                                     
                         Claim 1 is directed to a recombinant gene which comprises a nucleotide sequence                                         
                                                3                                                                                                
                 which encodes a flagellin  fusion protein.  In order to encode a fusion protein, the claimed                                    
                 recombinant gene requires two separate nucleotide sequences.  The first is a “flagellin                                         
                 sequence containing a first epitope of a flagellin structural gene.”  The second is one which                                   


                 As explained on pages 7-11 of the supporting specification, flagellin is a structural protein in bacterial3                                                                                                                              
                 flagella.                                                                                                                       
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