Appeal No. 1995-4717
Application 07/876,288
The references relied upon by the examiner are:
Cronan WO 90/14431 November 29, 1990
Devlin et al. (Devlin), "Random Peptide Libraries: A Source of Specific Protein Binding
Molecules," Science, vol. 249, pp. 404-406, 1990.
Scott et al. (Scott), "Searching for Peptide Ligands with an Epitope Library," Science, vol
249, pp. 386-390, 1990.
Maina et al. (Maina), "An Escherichia coli Vector to Express and Purify Foreign Proteins
by Fusion to and Separation from Maltose Binding Protein," Gene, vol. 74, pp. 365-373,
1988.
Plückthun et al. (Plückthun), "The Rationality of Random Screening-Efficient Methods of
Selection of Peptides and Oligonucleotide Ligands," Angew. Chem. Int. Ed. Engl., vol. 30,
no. 3, pp. 296-298, 1991.
Berg, "Zinc Fingers and Other Metal-Binding Domains," The Journal of Biological
Chemistry, vol. 265, no.12, pp. 6513-6516, 1990.
O'Neil et al. (O'Neil), "Design of DNA-Binding Peptides Based on Leucine Zipper Motif,"
Science, vol. 249, pp. 774-778, 1990.
GROUNDS OF RECORD
Claims 2 through 7 stand rejected under 35 U.S.C. § 112, second paragraph, as
failing to particularly point out and distinctly claim the invention.
Claims 1 through 5 and 24 stand rejected under 35 U.S.C. § 103. As evidence of
obviousness, the examiner relies upon Devlin, Cronan, Scott, Maina, and Plückthun.
Claims 6 through 7 stand rejected under 35 U.S.C. § 103. As evidence of
obviousness, the examiner relies upon Devlin, Cronan, Scott, Maina, Plückthun, Berg, and
O'Neil.
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