Ex parte HART - Page 8





              Appeal No. 1995-4717                                                                                     
              Application 07/876,288                                                                                   
              under 35 U.S.C. § 103.                                                                                   


              Claims 6 and 7:                                                                                          

                     In the rejection of claims 6 and 7 under 35 U.S.C. § 103 the examiner relies on the               
              references discussed above,  taken in further combination with Berg or O'Neil.  In view of               
              our determination regarding the previous rejection, it is only necessary to determine                    
              whether Berg or O'Neil provide that which is missing from the other references.   They do                
              not.  "Berg discloses the primary amino acid sequence and structure of the zinc finger                   
              containing peptides" (Answer, page 9) and "O'Neil et al. disclose the design of DNA-                     
              binding peptides wherein said peptides include leucine zipper motifs" including "the                     
              sequence of particular peptides that form leucine zippers . . . and the overall repeating                
              structure of leucine zipper containing peptides."  (Answer, paragraph bridging pages 9-                  
              10).  However, neither reference provides the reason, suggestion or motivation determined                
              to be missing and necessary to support the combination of the disclosure of the previously               
              discussed references.  Therefore, with regard to claims 6 and 7, we conclude that the                    
              examiner has failed to established a prima facie case of unpatentability of the claimed                  
              subject matter.  The rejection of claims 6 and 7 under 35 U.S.C. § 103 is reversed.                      






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