Ex parte KUHNE - Page 6




          Appeal No. 95-4791                                                           
          Application 08/034,849                                                       
          specification states (Spec., p. 2, l. 5-13):                                 
                    DE-OS 32 13 389, United States Patent No. 4,507,285                
               and United States Patent No. 4,296,103, describe                        
               chemically-stabilized chlorite matrices which are                       
               suitable for an external or oral therapeutic use.                       
               Besides various bacterial infections, the external                      
               treatment of virus infections, such as herpes simplex                   
               and herpes zoster, is deemed possible in this manner but                
               an intravenous administration for the treatment of HIV                  
               infections is not possible.                                             
               B.   Kuhne I and Kuhne II5                                              
               Canadian Patent 1,268,714 (Canada) describes “the use of                
          a composition consisting of an aqueous solution of a                         
          chemically stabilized chlorite matrix for intravenous and                    
          topical administration in tumor treatments” (Canada, p. 1, l.                
          13-16).  Isotonic solutions of stabilized chlorite matrices                  


               in cosmetics, for the sterilization of food and                         
               drinking water, and as feed additives.  General                         
               areas of medical application are to be found in                         
               the fields of disinfectants and chemoprophylaxis.                       
               The stabilized activated oxygen according to the                        
               invention can especially be used, for example, for                      
               the treatment of skin diseases such as herpes simples                   
               [sic], herpes zoster, acne or burns, or wound healing                   
               disorders or for macrophage and phagocyte stimulation.                  
               In particular, an arteriopathy and an alopecia areata                   
               can be influenced significantly.  With melanomes [sic]                  
               significant remissions have been obtained.                              
              5    We consider Canadian Patent 1,268,714 to be an                     
          English translation of EP-200,156 and Australia 599,027 to be                
          an English translation of EP-200,157.  We cite the English                   
          publications.                                                                
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