Ex parte KUHNE - Page 11




          Appeal No. 95-4791                                                           
          Application 08/034,849                                                       
          infections.  See page 2, l. 22-27, of appellant’s                            
          specification and page 1064, phagocyte, of Stedman’s Medical                 
          Dictionary, 24th Edition, Williams & Wilkins, Baltimore, MD                  
          (1982)(attached).                                                            
               Third, we find that the physiological activity of the HIV               
          virus is sufficiently unpredictable and so distinct from that                
          of bacteria that persons having ordinary skill in the art                    
          reasonably would not have expected to be able to successfully                
          treat                                                                        
          subjects infected by the HIV virus using a procedure found to                
          be successful for treating bacteria.  Little correlation                     
          between success in treating the HIV virus and success in                     
          treating other RNA viruses has been found.  See the Discussion               
          in In re Wright, 999 F.2d 1557, 1561-1564, 27 USPQ2d 1510,                   
          1513-1515 (Fed. Cir. 1993).                                                  
               Fourth, the art has long sought and continues to search                 
          for suitable means and methods for successfully treating                     
          infection by the HIV virus.                                                  
               Fifth, appellant’s specification cites prior art which                  
          purports to teach that chlorine dioxide-liberating chlorites                 
          generally had been presumed to attack red blood cells and                    
          therefore had been considered unsuitable for treating                        
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