Appeal No. 1995-4903 Application No. 07/926,016 we conclude that it would have been obvious to the person having ordinary skill in the art to incorporate any pharmaceutically acceptable phosphonic acid known to be an anticalculus agent in the oral composition of Haefele(‘002). Accordingly, we sustain the rejection of the examiner. The Rejection Of Vinson And Ploger (I-II), With Irani, Gaffar, Parran, Henkel and Kanebo “[T]he examiner bears the initial burden, on review of the prior art or on any other ground, of presenting a prima facie case of unpatentability.” See In re Oetiker, 977 F.2d 1443, 1445, 24 USPQ2d 1443, 1444 (Fed. Cir. 1992). The examiner relies upon a combination of up to eleven references to reject the claimed subject matter and establish a prima facie case of obviousness. The basic premise of the rejection is that the primary reference to Vinson discloses an oral care composition containing an anticalculus mixture having present triclosan (component (b)) as one of the antibacterial agents taught therein. The Ploger references disclose the azacycloalkane diphosphonic acid which constitute component (a), and the balance of the references provide motivation for 15Page: Previous 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NextLast modified: November 3, 2007