Ex parte DAVIS et al. - Page 4




          Appeal No. 95-5069                                                          
          Application No. 08/202,055                                                  


          Mammalian Cell," 34 The Journal of Biological Chemistry 15936-              
          40 (Dec. 5, 1986)                                                           
          Frances M. Platt et al. (Platt), "Modulation of cell-surface                
          transferrin receptor by the imino sugar N-                                  
          butyldeoxynojirimycin," 208 European Journal of Biochemistry                
          no. 1, 187-93 (Aug. 92)                                                     
               In rejecting the appealed claims on prior art grounds,                 
          the examiner relies on these references:                                    
          Fleet et al. (Fleet)           4,849,430            Jul. 18, 1989           
          Po-Ying Chan and Timothy A. Springer (Chan), "Effect of                     
          Lengthening Lymphocyte Function-Associated Antigen 3 on                     
          Adhesion to CD2,                                                            
          3 Molecular Biology of the Cell 157-66 (Feb. 1992)                          
          E. Yvonne Jones et al. (Jones), "Crystal structure at 2.8 D                 
          resolution of a soluble form of the cell adhesion molecule                  
          CD2," 360 Nature 232-39 (Nov. 19, 1992)                                     


                                   THE REJECTIONS                                     
               Claims 1, 4, and 5 stand rejected under 35 U.S.C. § 112,               
          first paragraph, as based on a non-enabling disclosure.  As                 
          evidence supporting this ground of rejection, the examiner                  
          relies on Peyrieras, Platt, and Romero.  Claims 1, 4, and 5                 
          further stand rejected under 35 U.S.C. § 103.  As evidence                  
          supporting this ground of rejection, the examiner relies on                 
          the combined disclosures of Jones, Chan, and Fleet.                         


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