Ex parte DAVIS et al. - Page 7




          Appeal No. 95-5069                                                          
          Application No. 08/202,055                                                  


          Du Pont DeNemours & Co., 750 F.2d 1569, 1576-77, 224 USPQ 409,              
          414 (Fed. Cir. 1984):                                                       
               Even if some of the claimed combinations were                          
               inoperative, the claims are not necessarily invalid.                   
               "It is not a function of the claims to specifically                    
               exclude . . . possible inoperative substances . . .                    
               ." Of course, if the number of inoperative                             
               combinations becomes significant, and in effect                        
               forces one of ordinary skill in the art to                             
               experiment unduly in order to practice the claimed                     
               invention, the claims might indeed be invalid.                         
               That, however, has not been shown to be the case                       
               here.  [Citations omitted].                                            
          On this record, the examiner has not established that the                   
          number of inoperative glycoproteins encompassed by claims 1,                
          4, and 5 is significant or "in effect forces one of ordinary                
          skill in the art to experiment unduly in order to practice the              
          claimed invention."  The examiner sets forth a conclusory                   
          statement that "the specification fails to provide guidance as              
          to the appropriate glycoprotein features required for the                   
          operation of the system."  See the Examiner's Answer, page 4,               
          first full paragraph.  That, however, is a bald conclusion not              
          adequately supported by facts.  The examiner has not provided,              
          for the record, a fact-based analysis of the specification                  
          teachings.  We therefore reverse the rejection of claims 1, 4,              



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